The decrease in positive affect in the relatives was similar to that of the patients, while the increase in negative affect in this group was intermediary to that of patients and control subjects.Ĭonclusions Higher levels of familial risk for psychosis were associated with higher levels of emotional reactivity to daily life stress in a dose-response fashion. Patients with psychotic illness reacted with more intense emotions to subjective appraisals of stress in daily life than control subjects. However, the groups differed quantitatively in their pattern of reactions to stress. Results Multilevel regression analyses showed that an increase in subjective stress was associated with an increase in negative affect and a decrease in positive affect in all groups. Methods Patients with psychotic illness (n = 42), their first-degree relatives (n = 47), and control subjects (n = 49) were studied with the Experience Sampling Method (a structured diary technique assessing thoughts, current context, and mood in daily life) to assess (1) appraised subjective stress of daily events and smaller disturbances in daily life and (2) emotional reactivity conceptualized as changes in both negative affect and positive affect.
The present study investigated this interaction and studied emotional reactivity to daily life stress as a vulnerability marker for psychotic illness. Shared Decision Making and Communicationīackground The vulnerability-stress model of psychotic disorders describes, in essence, an interaction between personal vulnerability and environmental stressors.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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